Wednesday, August 18, 2010

New investigate questions benefits of elective removal of ovaries during hysterectomy



Philadelphia, PA, Mar 9, 2010 -- Removal of the ovaries (bilateral oophorectomy) whilst behaving a hysterectomy is usual use to forestall the successive growth of ovarian cancer. This preventative procession is achieved in 55% of all U.S. women carrying a hysterectomy, or we estimate 300,000 times each year. An essay in the March/April issue of The Journal of Minimally Invasive Gynecology suggests that this procession might do some-more mistreat than good.

William H. Parker, MD, John Wayne Cancer Institute at Saint John"s Health Center, Santa Monica, CA, provides a extensive research of the healing novel relating to the great of oophorectomy at the time of hysterectomy. His review includes studies of post-hysterectomy cancer incidence, all means mortality, cardiovascular disease, osteoporosis and hip fractures, coronary blood vessel disease, and a series of alternative conditions. He concludes that, on balance, removal of the ovaries is not in all fitting for all women undergoing hysterectomy. In women not at high risk for growth of ovarian or breast cancer, stealing the ovaries at the time of hysterectomy should be approached with caution.

Dr. Parker states, "Presently, observational studies indicate that shared oophorectomy might do some-more mistreat than good. Given that 300 000 U.S. women a year bear elective oophorectomy, the commentary of increasing long-term risks have critical open health implications?Prudence suggests that a minute sensitive agree routine covering the risks and benefits of oophorectomy and ovarian charge should be conducted with women faced with this critical decision."

Premenopausal oophorectomy causes a fast decrease in present ovarian estrogens and androgens. Postmenopausal ovaries go on to furnish poignant amounts of the androgens testosterone and androstenedione, that are converted to estrogen. Estrogen scarcity has been compared with higher risks of coronary blood vessel disease and hip fracture, and neurologic conditions. Although we estimate 15,000 U.S. women die each year of ovarian cancer, 350,000 women die of coronary blood vessel disease. Therefore shortening a woman"s risk of ovarian cancer with oophorectomy might be outweighed by increasing risks of coronary blood vessel disease and neurologic conditions.

In an concomitant editorial, G. David Adamson, MD, FRCSC, FACOG, FACS, Director of Fertility Physicians of Northern California, Palo Alto and San Jose, CA, and past-president of both the American Society for Reproductive Medicine and the American Association of Gynecologic Laparoscopists, comments, "Dr. Parker has achieved a profitable use to his associate gynecologists and to women everywhere who have to have the formidable preference per ovarian charge or removal at the time of hysterectomy. Oophorectomy is not indispensably the wrong preference for most women, but comment of these interpretation leads to the end that some-more women are undergoing oophorectomy than should."

The essay is "Bilateral Oophorectomy contra Ovarian Conservation: Effects on Long-term Women"s Health" by William H. Parker, MD. The paper is "Ovarian Conservation" by G. David Adamson, MD. Both crop up in the Journal of Minimally Invasive Gynecology, Volume 17, Number 2 (March/April 2010) published by Elsevier.

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http://www.elsevierhealth.com

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